ipc298 cell line Search Results


cancer cell lines  (ATCC)
99
ATCC cancer cell lines
Cancer Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cancer cell lines/product/ATCC
Average 99 stars, based on 1 article reviews
cancer cell lines - by Bioz Stars, 2026-03
99/100 stars
  Buy from Supplier
cell culture cell lines  (ATCC)
96
ATCC cell culture cell lines
Cell Culture Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell culture cell lines/product/ATCC
Average 96 stars, based on 1 article reviews
cell culture cell lines - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier
ipc 298 cell line  (DSMZ)
93
DSMZ ipc 298 cell line
Ipc 298 Cell Line, supplied by DSMZ, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ipc 298 cell line/product/DSMZ
Average 93 stars, based on 1 article reviews
ipc 298 cell line - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
ipc-298 cell line  (DSMZ)
90
DSMZ ipc-298 cell line
Ipc 298 Cell Line, supplied by DSMZ, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ipc-298 cell line/product/DSMZ
Average 90 stars, based on 1 article reviews
ipc-298 cell line - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
cell lines  (ATCC)
99
ATCC cell lines
Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cell lines/product/ATCC
Average 99 stars, based on 1 article reviews
cell lines - by Bioz Stars, 2026-03
99/100 stars
  Buy from Supplier
ipc298 cell line  (Array BioPharma)
90
Array BioPharma ipc298 cell line
Ipc298 Cell Line, supplied by Array BioPharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ipc298 cell line/product/Array BioPharma
Average 90 stars, based on 1 article reviews
ipc298 cell line - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
skmel28 cell line  (Array BioPharma)
90
Array BioPharma skmel28 cell line
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Skmel28 Cell Line, supplied by Array BioPharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/skmel28 cell line/product/Array BioPharma
Average 90 stars, based on 1 article reviews
skmel28 cell line - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
novaseq control software v.1.6.0  (Illumina Inc)
90
Illumina Inc novaseq control software v.1.6.0
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Novaseq Control Software V.1.6.0, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/novaseq control software v.1.6.0/product/Illumina Inc
Average 90 stars, based on 1 article reviews
novaseq control software v.1.6.0 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
belvarafenib-resistant ipc-298 cell lines  (Genentech inc)
90
Genentech inc belvarafenib-resistant ipc-298 cell lines
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Belvarafenib Resistant Ipc 298 Cell Lines, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/belvarafenib-resistant ipc-298 cell lines/product/Genentech inc
Average 90 stars, based on 1 article reviews
belvarafenib-resistant ipc-298 cell lines - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
invasion human malignant melanoma cell lines  (ATCC)
99
ATCC invasion human malignant melanoma cell lines
(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for <t>IPC298</t> CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.
Invasion Human Malignant Melanoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/invasion human malignant melanoma cell lines/product/ATCC
Average 99 stars, based on 1 article reviews
invasion human malignant melanoma cell lines - by Bioz Stars, 2026-03
99/100 stars
  Buy from Supplier

Image Search Results


(A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for IPC298 CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.

Journal: bioRxiv

Article Title: MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

doi: 10.1101/2022.01.10.475285

Figure Lengend Snippet: (A) Experimental setup for cell line xenograft studies of mice + binimetinib or encorafinib. X-axis describes days of therapy and drug treatment (M=MEKi, binimetinib and B=BRAFi, encorafinib). (B) Volcano plot, average fold change in pMHC expression with binimetinib treatment (n=3 biological replicates for DMSO and MEKi treated cells) versus significance (mean-adjusted p value, unpaired two-sided t test) for IPC298 CLX. (C) Violin plot of distribution of fold changes in presentation of pMHCs following MEK inhibition (M, binimetinib), BRAF inhibition (B, encorafinib) or both (B/M). Solid line represents median, dotted lines define the first and third quartiles. (D) TAA enrichment significance values for each analysis. Black dotted line represents p≥0.05, grey = p≥0.01. (E) Changes in pMHC expression for select melanoma differentiation antigens. Errors bars represent standard deviation when >1 peptide from each source protein was identified.

Article Snippet: SKMEL5, SKMEL28, SKMEL2, and IPC298 cell lines were used for cell line xenograft (CLX) analyses in collaboration with Array Biopharma.

Techniques: Expressing, Inhibition, Standard Deviation